Trial intelligence / Profile preview

DECIDE-MET: MET inhibitors versus immune checkpoint inhibitor-based therapy in advanced NSCLC with MET exon 14 skipping

jRCT1031260225Phase 3Recruiting

Sponsor
Japan Clinical Oncology Group
Start
Jun 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
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Overview

Phase 3, randomised trial of tepotinib, capmatinib and pembrolizumab in non-small cell lung cancer (NSCLC) (3 arms), sponsored by Japan Clinical Oncology Group. Primary endpoint: overall survival. Started Jun 2026; status: recruiting.

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Drugs

tepotinibcapmatinibpembrolizumab
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Conditions

non-small cell lung cancer (NSCLC)

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