Trial intelligence / Profile preview

TPF neoadjuvant chemotherapy to enable minimally invasive surgery without routine adjuvant radiotherapy for HPV-positive oropharyngeal cancer

jRCT1041220029Active, not recruiting

Sponsor
Japan Agency for Medical Research and Development
Start
Oct 2022
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
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Overview

Open-label, single-arm trial of docetaxel, cisplatin and fluorouracil in oropharyngeal squamous cell carcinoma (OPSCC), sponsored by Japan Agency for Medical Research and Development. Primary endpoint: Pathological complete response rate. Started Oct 2022; status: active, not recruiting.

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Drugs

docetaxelcisplatinfluorouracil
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Conditions

oropharyngeal squamous cell carcinoma (OPSCC)

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