Trial intelligence / Profile preview

Cyclon-Asc observational study of deep molecular response and CTL clonality in chronic phase CML treated with asciminib

jRCT1070250023Recruiting

Sponsor
Tatsuro Jo
Start
May 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Open-label, single-arm trial of asciminib in chronic myelogenous leukemia (CML), sponsored by Tatsuro Jo. Primary endpoints: Changes in molecular response during asciminib treatment and Acquisition and transition of memory cytotoxic T lymphocytes during asciminib treatment. Started May 2025; status: recruiting.

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Drugs

asciminib
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Conditions

chronic myelogenous leukemia (CML)

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