Trial intelligence / Profile preview

AURORA ctDNA-positive adjuvant chemotherapy trial after curative resection of metastatic colorectal cancer

jRCT1071220087Phase 2Recruiting

Sponsor
Guardant Health
Start
Jan 2023
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of bevacizumab, fluorouracil, folinic acid, oxaliplatin and irinotecan in colorectal cancer (CRC) (2 arms), sponsored by Guardant Health. Primary endpoint: ctDNA negative conversion rate. Started Jan 2023; status: recruiting.

02

Drugs

bevacizumabfluorouracilfolinic acidoxaliplatinirinotecan
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Conditions

colorectal cancer (CRC)

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