Trial intelligence / Profile preview

Observational study of treatment persistence of acalabrutinib ± obinutuzumab in treatment-naive B-CLL

jRCT1071250076Recruiting

Sponsor
AstraZeneca
Start
Oct 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Open-label trial of acalabrutinib and obinutuzumab in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) (2 arms), sponsored by AstraZeneca. Primary endpoint: Discontinuation-free survival at 2 years. Started Oct 2025; status: recruiting.

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Drugs

acalabrutinibobinutuzumab
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Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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