Trial intelligence / Profile preview

TRANSFORM: Lisocabtagene maraleucel vs Standard of Care in Second-line Transplant-eligible Aggressive B-cell Lymphoma

jRCT1080224646Phase 2Completed

Sponsor
Bristol Myers Squibb
Start
Apr 2019
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
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Overview

Phase 2, randomised trial in diffuse large B-cell lymphoma (DLBCL), large-cell lymphoma, primary mediastinal large B-cell lymphoma (PMBCL) and 3 more comparing Lisocabtagene maraleucel arm with Standard of care arm (2 arms). Started Apr 2019; status: completed.

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Drugs

lisocabtagene maraleucel
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Conditions

diffuse large B-cell lymphoma (DLBCL)large-cell lymphomaprimary mediastinal large B-cell lymphoma (PMBCL)T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL)follicular lymphoma (FL)

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