Trial intelligence / Profile preview

Platform Study of AB122-Based Treatments in Advanced Solid Tumors

jRCT2011210020Phase 1Recruiting

Sponsor
Taiho Pharmaceutical Co., Ltd.
Start
Sep 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 1, open-label trial of zimberelimab in Nonhematologic neoplasms, pancreatic adenocarcinoma (PDAC), colorectal adenocarcinoma and 7 more (15 cohorts), sponsored by Taiho Pharmaceutical Co., Ltd. Primary endpoints: Dose-limiting toxicities during Cycle 1 (Phase 1a, all cohorts except D-4, D-5, D-9), Adverse events and treatment-related adverse events (Phase 1a, Cohorts D-4, D-5, D-9) and 2 more. Started Sep 2021; status: recruiting.

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Drugs

zimberelimab
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Conditions

Nonhematologic neoplasmspancreatic adenocarcinoma (PDAC)colorectal adenocarcinomanon-small cell lung cancer (NSCLC)gastric adenocarcinoma

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