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Mosunetuzumab + polatuzumab vedotin vs rituximab + GemOx in relapsed/refractory aggressive B-cell non-Hodgkin's lymphoma

jRCT2011220013Phase 3Active, not recruiting

Sponsor
Chugai Pharmaceutical Co., Ltd.
Start
Sep 2022
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
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Overview

Phase 3, randomised, open-label trial of mosunetuzumab in non-Hodgkin lymphoma (NHL), diffuse large B-cell lymphoma (DLBCL), large-cell lymphoma and 2 more (2 arms), sponsored by Chugai Pharmaceutical Co., Ltd. Started Sep 2022; status: active, not recruiting.

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Drugs

mosunetuzumab
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Conditions

non-Hodgkin lymphoma (NHL)diffuse large B-cell lymphoma (DLBCL)large-cell lymphomafollicular lymphoma, transformed (t-FL)follicular lymphoma (FL)

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