Trial intelligence / Profile preview

BENITO: MB12 vs Keytruda with chemotherapy in advanced non-squamous NSCLC

jRCT2011240078Recruiting

Sponsor
Chemical Biology Research
Start
Jul 2025
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
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Overview

Randomised, double-blind trial in Non-small cell lung cancer (NS-NSCLC) comparing MB12 + chemotherapy with Keytruda + chemotherapy (2 arms). Primary endpoints: AUC0-504 between Cycle 1 and Cycle 2 and AUCss between Cycle 7 and Cycle 8. Started Jul 2025; status: recruiting.

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Drugs

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Conditions

Non-small cell lung cancer (NS-NSCLC)

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