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Phase 2 single-arm INCB123667 in platinum-resistant ovarian cancer with cyclin E1 overexpression

jRCT2011250028Phase 2Recruiting

Sponsor
Incyte
Start
Nov 2025
Modality
Small Molecules
01

Overview

Phase 2, open-label trial of INCB123667 in high-grade serous carcinoma (HGSC), High-grade serous carcinoma of the fallopian tube (HGSC), primary peritoneal cancer (PPC) and 1 more (3 cohorts), sponsored by Incyte. Primary endpoint: Objective Response by IRC. Started Nov 2025; status: recruiting.

02

Drugs

INCB123667
03

Conditions

high-grade serous carcinoma (HGSC)High-grade serous carcinoma of the fallopian tube (HGSC)primary peritoneal cancer (PPC)ovarian cancer

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