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Velzatinib versus imatinib in previously untreated metastatic or unresectable GIST

jRCT2011260011Phase 3Recruiting

Sponsor
GSK
Start
Aug 2026
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial in gastrointestinal stromal tumor (GIST) comparing Velzatinib arm with Imatinib arm (2 arms). Primary endpoint: Progression-Free Survival. Started Aug 2026; status: recruiting.

02

Drugs

IDRX-42imatinib
03

Conditions

gastrointestinal stromal tumor (GIST)

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