Trial intelligence / Profile preview

Rapcabtagene autoleucel vs active comparator in severe GPA/MPA

jRCT2013240076Phase 2Suspended

Sponsor
Novartis
Start
Mar 2025
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Vaccines & Immunotherapeutics, Gene Therapies
01

Overview

Phase 2, randomised, open-label trial of rapcabtagene autoleucel in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) (2 arms), sponsored by Novartis. Primary endpoint: Event-free survival. Started Mar 2025; status: suspended.

02

Drugs

rapcabtagene autoleucel
03

Conditions

granulomatosis with polyangiitis (GPA)microscopic polyangiitis (MPA)

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