Trial intelligence / Profile preview

Sabatolimab plus azacitidine and venetoclax in newly diagnosed AML patients unfit for intensive chemotherapy

jRCT2021210050Phase 2Completed

Sponsor
Novartis
Start
Nov 2021
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
01

Overview

Phase 2, open-label, single-arm trial of sabatolimab, venetoclax and azacitidine in acute myeloid leukemia (AML), sponsored by Novartis. Primary endpoints: Incidence of dose-limiting toxicities and Complete remission rate. Started Nov 2021; status: completed.

02

Drugs

sabatolimabvenetoclaxazacitidine
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Conditions

acute myeloid leukemia (AML)

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