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ADAPT Forward 1: empasiprubart add-on to efgartigimod in AChR-antibody positive generalized myasthenia gravis
jRCT2021260014Phase 2Recruiting
- Sponsor
- argenx
- Start
- Jun 2026
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
01
Overview
Phase 2, open-label, single-arm trial of empasiprubart and efgartigimod alfa in myasthenia gravis (MG), sponsored by argenx. Primary endpoints: Incidence, severity, and relatedness of adverse events and serious adverse events and Clinically meaningful changes in vital signs, ECGs, and laboratory parameters. Started Jun 2026; status: recruiting.
02
Drugs
empasiprubartefgartigimod alfa
03
Conditions
myasthenia gravis (MG)
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