Trial intelligence / Profile preview

INTerpath-014 adjuvant intismeran with or without MK-3475A versus placebo in resected high-risk stage I NSCLC

jRCT2021260028Phase 3Recruiting

Sponsor
Merck & Co.
Start
Sep 2026
Modality
Therapeutic Enzymes → Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics, Vaccines & Immunotherapeutics
01

Overview

Phase 3, randomised, double-blind trial of intismeran autogene and berahyaluronidase alfa + pembrolizumab in non-small cell lung cancer (NSCLC) (3 arms), sponsored by Merck & Co. Primary endpoint: Disease-free survival. Started Sep 2026; status: recruiting.

02

Drugs

intismeran autogeneberahyaluronidase alfa + pembrolizumab
03

Conditions

non-small cell lung cancer (NSCLC)

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