Trial intelligence / Profile preview

Empasiprubart IV Monotherapy in AChR Antibody–Positive Generalized Myasthenia Gravis (Master Protocol ARGX-999-2-MG-2000, ISA2)

jRCT2021260031Phase 2Recruiting

Sponsor
argenx
Start
Aug 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
01

Overview

Phase 2, randomised, double-blind trial in myasthenia gravis (MG) comparing Empasiprubart IV monotherapy with Placebo IV (2 arms). Primary endpoints: MP primary safety endpoints and ISA2 primary safety endpoints (double-blinded treatment period). Started Aug 2026; status: recruiting.

02

Drugs

empasiprubart
03

Conditions

myasthenia gravis (MG)

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