Trial intelligence / Profile preview

TROPION-Lung02: datopotamab deruxtecan with pembrolizumab with or without platinum chemotherapy in advanced or metastatic non-small cell lung cancer

jRCT2031200193Phase 1Active, not recruiting

Sponsor
Daiichi Sankyo Co., Ltd.
Start
Dec 2020
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
01

Overview

Phase 1, open-label trial of datopotamab deruxtecan, pembrolizumab, carboplatin and cisplatin in non-small cell lung cancer (NSCLC) (3 arms), sponsored by Daiichi Sankyo Co., Ltd. Primary endpoint: Number of participants with dose-limiting toxicities and treatment-emergent adverse events. Started Dec 2020; status: active, not recruiting.

02

Drugs

datopotamab deruxtecanpembrolizumabcarboplatincisplatin
03

Conditions

non-small cell lung cancer (NSCLC)

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