Trial intelligence / Profile preview

MARGARET phase I/II study of TAS0953/HM06 in RET-altered advanced solid tumors

jRCT2031200208Phase 2Recruiting

Sponsor
Taiho Pharmaceutical Co., Ltd.
Start
Feb 2021
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
01

Overview

Phase 2, open-label trial of vepafestinib in Nonhematologic neoplasms and non-small cell lung cancer (NSCLC) (8 arms), sponsored by Taiho Pharmaceutical Co., Ltd. Primary endpoints: Maximum Tolerated Dose, Recommended Phase 2 Dose and 1 more. Started Feb 2021; status: recruiting.

02

Drugs

vepafestinib
03

Conditions

Nonhematologic neoplasmsnon-small cell lung cancer (NSCLC)

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