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POD1UM-303/InterAACT 2: Retifanlimab plus carboplatin-paclitaxel in inoperable locally recurrent or metastatic anal canal squamous cell carcinoma

jRCT2031200380Phase 3Completed

Sponsor
Incyte
Start
Apr 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, double-blind trial in anal squamous cell carcinoma (SCCA) comparing Group A: carboplatin + paclitaxel + placebo with Group B: carboplatin + paclitaxel + retifanlimab (2 arms). Primary endpoint: Progression-free survival (PFS). Started Apr 2021; status: completed.

02

Drugs

retifanlimab
03

Conditions

anal squamous cell carcinoma (SCCA)

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