Trial intelligence / Profile preview

MATTERHORN trial of perioperative durvalumab plus FLOT in resectable gastric and gastroesophageal junction cancer

jRCT2031210307Active, not recruiting

Sponsor
AstraZeneca
Start
Jan 2021
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
01

Overview

Randomised, double-blind trial of durvalumab, fluorouracil, folinic acid, oxaliplatin and docetaxel in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma (2 arms), sponsored by AstraZeneca. Primary endpoint: Event-free survival. Started Jan 2021; status: active, not recruiting.

02

Drugs

durvalumabfluorouracilfolinic acidoxaliplatindocetaxel
03

Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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