Trial intelligence / Profile preview

BLU-945 phase 1/2 study in EGFR-mutant non-small cell lung cancer

jRCT2031210431Phase 2Completed

Sponsor
Blueprint Medicines
Start
Dec 2021
Modality
Small Molecules
01

Overview

Phase 2, open-label trial of tigozertinib and osimertinib in non-small cell lung cancer (NSCLC) (6 arms), sponsored by Blueprint Medicines. Primary endpoints: Maximum tolerated dose determination of BLU-945 monotherapy and BLU-945 plus osimertinib, Recommended phase 2 dose determination and 2 more. Started Dec 2021; status: completed.

02

Drugs

tigozertinibosimertinib
03

Conditions

non-small cell lung cancer (NSCLC)

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