Trial intelligence / Profile preview

Phase 1 Dose Escalation and Expansion Study of PF-07265028 ± Sasanlimab in Advanced Solid Tumors

jRCT2031210676Phase 1Completed

Sponsor
Pfizer
Start
Mar 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
2
01

Overview

Phase 1, open-label trial of pf-07265028 and sasanlimab in Nonhematologic neoplasms, gastric cancer (GC), esophagogastric junction cancer and 3 more (2 arms), sponsored by Pfizer. Primary endpoints: Dose-limiting toxicities in Dose Escalation (Part 1), Adverse events and 2 more. Started Mar 2022; status: completed.

02

Drugs

pf-07265028sasanlimab
03

Conditions

Nonhematologic neoplasmsgastric cancer (GC)esophagogastric junction cancerhead and neck squamous cell carcinoma (HNSCC)transitional cell carcinoma (TCC)

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