Trial intelligence / Profile preview

NEXUS study of perioperative encorafenib + binimetinib + cetuximab for resectable BRAF V600E-mutant colorectal metastasis

jRCT2031220025Active, not recruiting

Sponsor
Japan Agency for Medical Research and Development
Start
Sep 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Open-label, single-arm trial of encorafenib, binimetinib and cetuximab in colorectal cancer (CRC) and metastatic colorectal adenocarcinoma (mCRC), sponsored by Japan Agency for Medical Research and Development. Primary endpoint: 1-year progression-free survival. Started Sep 2022; status: active, not recruiting.

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Drugs

encorafenibbinimetinibcetuximab
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Conditions

colorectal cancer (CRC)metastatic colorectal adenocarcinoma (mCRC)

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