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PROPEL-36 bempegaldesleukin + pembrolizumab vs pembrolizumab in first-line PD-L1+ metastatic/recurrent HNSCC

jRCT2031220385Phase 3Active, not recruiting

Sponsor
Nektar Therapeutics
Start
Oct 2022
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytokines & Interferons → Recombinant Proteins and Enzymes
01

Overview

Phase 3, randomised, open-label trial in head and neck squamous cell carcinoma (HNSCC) comparing bempegaldesleukin + pembrolizumab with pembrolizumab monotherapy (2 arms). Primary endpoints: Overall survival and Objective response rate. Started Oct 2022; status: active, not recruiting.

02

Drugs

bempegaldesleukinpembrolizumab
03

Conditions

head and neck squamous cell carcinoma (HNSCC)

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