Trial intelligence / Profile preview

VOLTAGE-2: Nivolumab With Selective Use of Chemoradiotherapy and Surgery in dMMR/MSI-H Rectal Cancer

jRCT2031220484Active, not recruiting

Sponsor
Japan Agency for Medical Research and Development
Start
Jan 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Open-label trial of nivolumab in rectal adenocarcinoma (2 cohorts), sponsored by Japan Agency for Medical Research and Development. Primary endpoint: 2-year clinical complete response (cCR) rate with nivolumab alone (investigator assessment). Started Jan 2023; status: active, not recruiting.

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Drugs

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Conditions

rectal adenocarcinoma

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