Trial intelligence / Profile preview

AVANZAR phase III first-line NSCLC study

jRCT2031220612Phase 3Active, not recruiting

Sponsor
AstraZeneca
Start
Feb 2023
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
01

Overview

Phase 3, randomised, open-label trial of datopotamab deruxtecan, durvalumab, carboplatin and pembrolizumab in non-small cell lung cancer (NSCLC) (2 arms), sponsored by AstraZeneca. Primary endpoints: Progression-Free Survival and Overall Survival. Started Feb 2023; status: active, not recruiting.

02

Drugs

datopotamab deruxtecandurvalumabcarboplatinpembrolizumab
03

Conditions

non-small cell lung cancer (NSCLC)

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