Trial intelligence / Profile preview

Phase Ia/Ib dose-escalation study of ROSE12 alone and with immune checkpoint inhibitors in advanced solid tumors

jRCT2031230072Phase 1Recruiting

Sponsor
Chugai Pharmaceutical Co., Ltd.
Start
May 2023
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
2
01

Overview

Phase 1, open-label trial of ROSE12 in Nonhematologic neoplasms, non-small cell lung cancer (NSCLC) and colorectal cancer (CRC) (3 arms), sponsored by Chugai Pharmaceutical Co., Ltd. Primary endpoints: Safety and tolerability of ROSE12, Anti-tumor activity of ROSE12 and 1 more. Started May 2023; status: recruiting.

02

Drugs

ROSE12
03

Conditions

Nonhematologic neoplasmsnon-small cell lung cancer (NSCLC)colorectal cancer (CRC)

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