Trial intelligence / Profile preview

Phase II multi-arm study of volrustomig, rilvegostomig, and AZD0901 combinations in gastric or GEJ adenocarcinoma

jRCT2031230074Phase 2Recruiting

Sponsor
AstraZeneca
Start
Jul 2023
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
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Overview

Phase 2, open-label trial of volrustomig, rilvegostomig and sonesitatug vedotin in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma (9 arms), sponsored by AstraZeneca. Primary endpoints: Objective response rate (ORR) and Progression-free survival (PFS). Started Jul 2023; status: recruiting.

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Drugs

volrustomigrilvegostomigsonesitatug vedotin
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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