Trial intelligence / Profile preview

VERITAC-3: ARV-471 (Vepdegestrant) plus Palbociclib vs Letrozole plus Palbociclib in ER+/HER2- Advanced Breast Cancer

jRCT2031230255Phase 3Active, not recruiting

Sponsor
Pfizer
Start
Aug 2023
Modality
PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
01

Overview

Phase 3, randomised, open-label trial of vepdegestrant in breast cancer (2 arms), sponsored by Pfizer. Started Aug 2023; status: active, not recruiting.

02

Drugs

vepdegestrant
03

Conditions

breast cancer

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