Trial intelligence / Profile preview

Phase 1 study of MK-2870 alone and with pembrolizumab in advanced solid tumors

jRCT2031230356Phase 1Active, not recruiting

Sponsor
Merck & Co.
Start
Oct 2023
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 1, open-label trial of sacituzumab tirumotecan and pembrolizumab in Nonhematologic neoplasms and non-small cell lung cancer (NSCLC) (2 arms), sponsored by Merck & Co. Primary endpoints: Safety and tolerability and Objective response rate. Started Oct 2023; status: active, not recruiting.

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Drugs

sacituzumab tirumotecanpembrolizumab
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Conditions

Nonhematologic neoplasmsnon-small cell lung cancer (NSCLC)

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