Trial intelligence / Profile preview

TAK-676 (dazostinag) alone and with pembrolizumab in advanced solid tumors

jRCT2031230532Phase 2Completed

Sponsor
Takeda
Start
Jul 2020
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
01

Overview

Phase 2, open-label trial of dazostinag and pembrolizumab in Nonhematologic neoplasms, head and neck squamous cell carcinoma (HNSCC) and colorectal cancer (CRC) (9 arms), sponsored by Takeda. Primary endpoints: Number of participants reporting one or more treatment-emergent adverse events, Number of participants with dose-limiting toxicities and 2 more. Started Jul 2020; status: completed.

02

Drugs

dazostinagpembrolizumab
03

Conditions

Nonhematologic neoplasmshead and neck squamous cell carcinoma (HNSCC)colorectal cancer (CRC)

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