Trial intelligence / Profile preview

HARMONi-3: ivonescimab plus chemotherapy versus pembrolizumab plus chemotherapy in first-line metastatic non-small cell lung cancer

jRCT2031230688Phase 3Active, not recruiting

Sponsor
Summit Therapeutics
Start
May 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
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Overview

Phase 3, randomised, double-blind trial of ivonescimab and pembrolizumab in non-small cell lung cancer (NSCLC) (3 arms), sponsored by Summit Therapeutics. Primary endpoints: Safety assessment, Pharmacokinetics and 2 more. Started May 2024; status: active, not recruiting.

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Drugs

ivonescimabpembrolizumab
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Conditions

non-small cell lung cancer (NSCLC)

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