Trial intelligence / Profile preview

MK-2870 vs chemotherapy in previously treated nonsquamous EGFR-mutant NSCLC

jRCT2031240108Phase 3Active, not recruiting

Sponsor
Merck & Co.
Start
Jul 2024
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
01

Overview

Phase 3, randomised, open-label trial of sacituzumab tirumotecan in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Merck & Co. Primary endpoints: Progression-Free Survival in EGFR-mutated NSCLC and Overall Survival in EGFR-mutated NSCLC. Started Jul 2024; status: active, not recruiting.

02

Drugs

sacituzumab tirumotecan
03

Conditions

non-small cell lung cancer (NSCLC)

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