Trial intelligence / Profile preview

Epcoritamab with or without lenalidomide versus R-GemOx in relapsed or refractory diffuse large B-cell lymphoma

jRCT2031240247Phase 3Active, not recruiting

Sponsor
AbbVie Inc.
Start
Aug 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
01

Overview

Phase 3, randomised, open-label trial in diffuse large B-cell lymphoma (DLBCL) comparing Epcoritamab Plus Lenalidomide, Rituximab Plus Gemcitabine and Oxaliplatin and Epcoritamab (3 arms). Primary endpoint: Progression-Free Survival. Started Aug 2024; status: active, not recruiting.

02

Drugs

epcoritamablenalidomiderituximabgemcitabineoxaliplatin
03

Conditions

diffuse large B-cell lymphoma (DLBCL)

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