Trial intelligence / Profile preview

VANGUARD: Atezolizumab plus Bevacizumab after Carbon Ion Radiotherapy in Hepatocellular Carcinoma

jRCT2031240284Phase 2Recruiting

Sponsor
Chugai Pharmaceutical Co., Ltd.
Start
Aug 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of atezolizumab and bevacizumab in hepatocellular carcinoma (HCC), sponsored by Chugai Pharmaceutical Co., Ltd. Primary endpoints: Dose-limiting toxicities (DLTs) proportion (Phase Ib) and 1-year recurrence-free survival rate (Phase II). Started Aug 2024; status: recruiting.

02

Drugs

atezolizumabbevacizumab
03

Conditions

hepatocellular carcinoma (HCC)

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