Trial intelligence / Profile preview

DREAMM-10: Belantamab mafodotin + lenalidomide + dexamethasone vs daratumumab + lenalidomide + dexamethasone in transplant-ineligible newly diagnosed multiple myeloma

jRCT2031240542Phase 3Active, not recruiting

Sponsor
GSK
Start
Mar 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
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Overview

Phase 3, randomised, open-label trial of belantamab mafodotin in multiple myeloma (MM) (2 arms), sponsored by GSK. Primary endpoints: Progression-Free Survival (PFS) and Number of participants achieving MRD negative status. Started Mar 2025; status: active, not recruiting.

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Drugs

belantamab mafodotin
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Conditions

multiple myeloma (MM)

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