Trial intelligence / Profile preview

Phase 1a/1b Study of Pan-KRAS Inhibitor LY4066434 in KRAS-Mutant Solid Tumors

jRCT2031240563Phase 1Active, not recruiting

Sponsor
Eli Lilly and Company
Start
Jan 2025
Modality
Small Molecules
01

Overview

Phase 1, open-label trial of LY4066434 in Nonhematologic neoplasms and carcinoma (2 arms), sponsored by Eli Lilly and Company. Primary endpoints: Dose-limiting toxicities (DLTs), Treatment-emergent adverse events (TEAEs) and serious adverse events (SAEs) related to study drug and 1 more. Started Jan 2025; status: active, not recruiting.

02

Drugs

LY4066434
03

Conditions

Nonhematologic neoplasmscarcinoma

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