Trial intelligence / Profile preview

Ivosidenib plus durvalumab and gemcitabine/cisplatin in first-line IDH1-mutated cholangiocarcinoma

jRCT2031240643Phase 2Active, not recruiting

Sponsor
Servier
Start
Oct 2025
Modality
Small Molecules
01

Overview

Phase 2, open-label, single-arm trial of ivosidenib in cholangiocarcinoma (CCA), sponsored by Servier. Primary endpoints: Dose-limiting toxicities in Safety Lead-in Phase, Dose modifications in Safety Lead-in Phase and 1 more. Started Oct 2025; status: active, not recruiting.

02

Drugs

ivosidenib
03

Conditions

cholangiocarcinoma (CCA)

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