Trial intelligence / Profile preview

Phase 3 Study of Pacritinib vs Physician's Choice in Myelofibrosis with Severe Thrombocytopenia

jRCT2031240668Phase 3Active, not recruiting

Sponsor
Sobi
Start
Jun 2025
Modality
Small Molecules
01

Overview

Phase 3, randomised trial of pacritinib in myelofibrosis (MF), primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) and 1 more (2 arms), sponsored by Sobi. Primary endpoints: Spleen volume reduction ≥35% at Week 24 and Total symptom score reduction ≥50% at Week 24. Started Jun 2025; status: active, not recruiting.

02

Drugs

pacritinib
03

Conditions

myelofibrosis (MF)primary myelofibrosis (PMF)post-polycythemia vera myelofibrosis (PPV-MF)post-essential thrombocythemia myelofibrosis (PET-MF)

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