Trial intelligence / Profile preview

HARMONi-7: Ivonescimab vs pembrolizumab in first-line metastatic NSCLC with high PD-L1

jRCT2031250093Phase 3Recruiting

Sponsor
Summit Therapeutics
Start
Nov 2025
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, double-blind trial of ivonescimab in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Summit Therapeutics. Primary endpoints: Overall survival and Progression-free survival by IRRC. Started Nov 2025; status: recruiting.

02

Drugs

ivonescimab
03

Conditions

non-small cell lung cancer (NSCLC)

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