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Phase 1/2 first-in-human study of GSK5458514 in metastatic castration-resistant prostate cancer

jRCT2031250111Phase 2Recruiting

Sponsor
GSK
Start
Jun 2025
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

Phase 2, open-label, single-arm trial of GSK5458514 in metastatic castration-resistant prostate cancer (mCRPC), sponsored by GSK. Primary endpoints: Incidence of dose-limiting toxicities (DLTs) and Incidence and severity of adverse events. Started Jun 2025; status: recruiting.

02

Drugs

GSK5458514
03

Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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