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Phase 2 dose-ranging study of PF-07275315 in moderate-to-severe asthma

jRCT2031250163Phase 2Recruiting

Sponsor
Pfizer
Start
Aug 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 2, randomised, double-blind trial of tilrekimig in asthma (4 arms), sponsored by Pfizer. Primary endpoints: Change from baseline in pre-bronchodilator FEV1 at Week 12, Incidence of treatment-emergent adverse events, serious adverse events, and AEs/SAEs leading to treatment discontinuation and 3 more. Started Aug 2025; status: recruiting.

02

Drugs

tilrekimig
03

Conditions

asthma

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