Trial intelligence / Profile preview

ABBV-400 vs standard of care in post-adjuvant ctDNA-positive colorectal cancer with no radiographic evidence of disease

jRCT2031250247Phase 2Recruiting

Sponsor
AbbVie Inc.
Start
Jul 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
01

Overview

Phase 2, randomised, open-label trial in colorectal cancer (CRC) comparing ABBV-400 monotherapy with Standard of care / active surveillance (2 arms). Primary endpoint: Disease-free survival (DFS). Started Jul 2025; status: recruiting.

02

Drugs

telisotuzumab adizutecan
03

Conditions

colorectal cancer (CRC)

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