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CDR132L in heart failure with preserved ejection fraction and left ventricular hypertrophy
jRCT2031250304Phase 2Recruiting
- Sponsor
- Novo Nordisk
- Start
- Aug 2025
- Modality
- Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
01
Overview
Phase 2, randomised, double-blind trial of CDR132L in heart failure with preserved ejection fraction (HFpEF) (4 arms), sponsored by Novo Nordisk. Primary endpoint: Change in miR-132. Started Aug 2025; status: recruiting.
02
Drugs
CDR132L
03
Conditions
heart failure with preserved ejection fraction (HFpEF)
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