Trial intelligence / Profile preview

First-in-Human Study of STX-478 in Advanced Solid Tumors

jRCT2031250315Phase 1Recruiting

Sponsor
Eli Lilly and Company
Start
Dec 2025
Modality
Small Molecules
01

Overview

Phase 1, open-label trial of tersolisib in breast cancer, Nonhematologic neoplasms, gynecological cancer and 2 more (11 arms), sponsored by Eli Lilly and Company. Primary endpoint: Dose Limiting Toxicities within first 28 days. Started Dec 2025; status: recruiting.

02

Drugs

tersolisib
03

Conditions

breast cancerNonhematologic neoplasmsgynecological cancerendometrial cancer (EC)head and neck squamous cell carcinoma (HNSCC)

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