Trial intelligence / Profile preview

MOVE-Lp(a): Muvalaplin for Reduction of Major Adverse Cardiovascular Events in Adults with Elevated Lipoprotein(a)

jRCT2031250354Phase 3Recruiting

Sponsor
Eli Lilly and Company
Start
Oct 2025
Modality
Small Molecules
01

Overview

Phase 3, randomised, double-blind trial in lipoprotein(a) hyperlipoproteinemia (Lp(a)), atherosclerotic disease, coronary arteriosclerosis and 2 more comparing Muvalaplin with Placebo (2 arms). Primary endpoint: Time to first occurrence of any component of the MACE-4 composite endpoint. Started Oct 2025; status: recruiting.

02

Drugs

muvalaplin
03

Conditions

lipoprotein(a) hyperlipoproteinemia (Lp(a))atherosclerotic diseasecoronary arteriosclerosiscerebrovascular diseasearteriosclerosis obliterans

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