Trial intelligence / Profile preview

ABBV-706 plus atezolizumab versus standard of care in first-line extensive-stage small cell lung cancer

jRCT2031250359Phase 2Recruiting

Sponsor
AbbVie Inc.
Start
Dec 2025
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
01

Overview

Phase 2, randomised, open-label trial of turmetabart adizutecan, atezolizumab, etoposide, carboplatin and lurbinectedin in small cell lung cancer (SCLC) (6 arms), sponsored by AbbVie Inc. Primary endpoints: Number of Participants with Adverse Events and Progression-Free Survival (PFS). Started Dec 2025; status: recruiting.

02

Drugs

turmetabart adizutecanatezolizumabetoposidecarboplatinlurbinectedin
03

Conditions

small cell lung cancer (SCLC)

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