Trial intelligence / Profile preview

Phase I trial of af-001 in differentiated thyroid cancer

jRCT2031250472Phase 1Not yet recruiting

Sponsor
Alpha Fusion, Inc.
Start
Oct 2025
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Alpha Emitters → Radiopharmaceuticals
Countries
1
01

Overview

Phase 1, open-label trial of sodium astatide (211At) in papillary thyroid cancer (PTC), follicular carcinoma (FTC) and well-differentiated thyroid cancer (WDTC) (2 cohorts), sponsored by Alpha Fusion, Inc. Primary endpoints: Safety evaluations (Part Ia), Dose-limiting toxicities (DLTs) (Part Ia) and 2 more. Planned start Oct 2025; status: not yet recruiting.

02

Drugs

sodium astatide (211At)
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Conditions

papillary thyroid cancer (PTC)follicular carcinoma (FTC)well-differentiated thyroid cancer (WDTC)

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