Trial intelligence / Profile preview

RAINFOL-03: Rinatabart Sesutecan vs Investigator's Choice in Endometrial Cancer After Platinum and PD-(L)1 Therapy

jRCT2031250494Phase 3Recruiting

Sponsor
Genmab
Start
Nov 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
01

Overview

Phase 3, randomised, open-label trial of rinatabart sesutecan in endometrial cancer (EC) (2 arms), sponsored by Genmab. Primary endpoints: Progression-free Survival (PFS) per RECIST v1.1 by Blinded Independent Central Review and Overall Survival (OS). Started Nov 2025; status: recruiting.

02

Drugs

rinatabart sesutecan
03

Conditions

endometrial cancer (EC)

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