Trial intelligence / Profile preview

Phase 2 Study of Solbinsiran (LY3561774) in Adults With Severe Hypertriglyceridemia

jRCT2031250567Phase 2Active, not recruiting

Sponsor
Eli Lilly and Company
Start
Jan 2026
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

Phase 2, randomised, double-blind trial in hypertriglyceridemia comparing Solbinsiran with Placebo (2 arms). Primary endpoint: Change from Baseline in Triglycerides. Started Jan 2026; status: active, not recruiting.

02

Drugs

solbinsiran
03

Conditions

hypertriglyceridemia

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